New studies link the environment to Parkinson's disease

Research will open new possibilities for intervention and prevention
Sunnyvale, CA – April 5, 2007 – The Parkinson's Institute today announced that new findings concerning the role of environmental factors in the development of Parkinson's disease will be reported at Asilomar (Pacific Grove, CA) as part of the final meeting of the Collaborative Centers for Parkinson's Disease Environmental Research (CCPDER). This collaborative research effort, sponsored by the National Institute of Environmental Health Sciences (NIEHS), brings together investigators from Emory University, the University of California Los Angeles and The Parkinson's Institute, which has served as the coordinating center for the study.
Highlights of the research include:
The role of pesticides (eg. Paraquat and Dieldrin) as potential risk factors for Parkinson's disease, a role suggested by both epidemiological statistics and laboratory evidence.
The threat of toxic agents to damage neurons by causing the accumulation of harmful proteins.
Intraneuronal protein aggregates as markers of Parkinson's pathology, based on work carried out at The Parkinson's Institute indicating that these aggregates could be formed as a consequence of toxic exposure.
The importance of targeting a specific protein, alpha-synuclein, in order to achieve neuroprotection in Parkinson's
The role of inflammation in the development of Parkinson's disease and the possibility that anti-inflammatory drugs could be beneficial to patients.
The possibility that nicotine may act as a neuroprotective agent.