Wednesday, October 30, 2019

Smart homes enhance seniors' safety



In Singapore, as well as many other countries, ensuring a high quality of life for an expanding elderly population demands that community eldercare providers strike a delicate balance between frequently competing factors. For instance, safety is sometimes at odds with privacy; providing comprehensive care may erode an elderly person's cherished sense of independence; and a sense of security may give rise to a sense of being controlled.
30 oct 2019--Project SHINESeniors, which is focused on resolving these contradictions, does so by creating a "smart home" for older people living alone. Driven by a research team at Singapore Management University (SMU)'s iCity Lab (co-founded by SMU and Tata Consultancy Services), the project is funded by the Singapore Ministry of National Development and National Research Foundation under the Land and Liveability National Innovation Challenge (L2NIC) grant.
As part of the three-year project, the team has equipped 50 one-bedroom apartments with motion sensors that can detect unusual periods of inactivity – a possible indication that the tenant has either fallen or suffered a health crisis. This information is then fed to a Voluntary Welfare Organisation (VWO) for its staff and volunteers to react to the potential emergency.
Although other projects in Singapore are testing similar technologies, what makes Project SHINESeniors unique is its focus on how the technological tools can enhance the efforts of community caregivers who provide the crucial, person-to-person contact with elderly tenants.
"What we are providing that's of value is tying the technology to care provisioning," says Associate Professor Tan Hwee Pink, Academic Director of iCity Lab. "We see it as a more complete, holistic, and end-to-end evidence-based approach to ageing. The technology enables community organisations to improve their operations and increase their effectiveness with the limited number of staff and volunteers they have, while still catering to the elderly person's individual needs."
Staying in place is preferable
The research proposes that the best approach to deal with a growth in an ageing population is to allow as many people to stay in their homes as possible.
With senior citizens set to account for 20 percent of Singapore's population by 2030, the concept of "ageing in place" becomes key to dealing with "the fact that healthcare resources and assisted living facilities are becoming more limited," says Professor Tan. "We don't want our population to be over-stressing the hospitals, and we want them to have a good quality-of-life in the community they are living in. That's why care is being moved away from the hospitals and nursing homes and into the community, with the help of community-based VWOs."
Interviews with participants of the iCity pilot project indicate that "most of the elderly prefer to be living by themselves rather than living in an assisted living facility," he says.
Yet, living alone is not without risk. In fact, the government initiated the current research in response to the tragic realisation that, over a five year period, "about 50 elderly residents in Singapore passed away in their homes, and it had taken days, or sometimes up to a few weeks, to find out that they were dead," according to Professor Tan.
To reduce such incidents, a sensor-enhanced "smart home" is designed. The first line of defense is a 'panic button' that a resident can push to alert the community caregivers that he or she has fallen or is facing some kind of problem. And if the elderly person is not carrying the panic button, there is still the sensor system to detect the conditions that point to an emergency, analyse the data, and sound the alarm.
Door contacts at the main door detect the opening and closing of doors, indicating whether the tenant is inside or outside the apartment. If the resident remains inside, motion sensors on the walls of each room will determine whether the person is moving according to normal patterns, or if there is an unexpected absence of movement.
SMU research fellow Dr. Alvin Valera says a common scenario that it is crucial to have the sensor system is when the resident has encountered trouble after entering the toilet.
"The reason we monitor inactivity," he explains, "is that there are situations where the person might not have access to the button. If the person is in the toilet and has fallen, he or she has probably left the panic button outside. In this case, the system will detect that the last activity was in the toilet and that there was no motion afterwards. After a certain period of inactivity, an alert will be sent to the caregivers."
Dr. Valera stresses that the "unobtrusive" nature of this motion-detecting system reassures residents that their privacy is not being violated.
"We don't use vision-based or camera-based sensors, or even those that record audio precisely because of this concern with privacy," he says. "The unobtrusiveness of the system means that elderly are much more likely to accept the technology. And because the sensors are passive—installed on the walls—they don't have to do anything to change their lifestyles."
Refining the system for scale-up
A key objective of the current iCity Lab pilot project is to refine the technology to distinguish better between normal and abnormal periods or inactivity, so as to reduce the number of false alarms.
"We want to make sure that alerts are sent in a timely way, so that they don't swamp the caregivers with false alerts," Dr. Valera explains. So we looked at the historical data of each resident's movement patterns to determine a personalized threshold that would give us a better indication of how long it should be before an alert is sent."
A second technological enhancement is a personalised, sensor-equipped medication box that is being tested in ten apartments. Unlike those off-the-shelf pillboxes, the 'sensorised' medication box has been customised to the needs and preferences (e.g. size and colour) of the individual user. Such customisation has been shown to be effective in encouraging elderly to use these technologically enhanced box.
"Whenever the person opens up the medication box, we can infer that medication has been taken," says SMU research scientist Dr. Tan Hwee Xian. "We are able to look at the frequency and timing of the medication intake, to determine if the elderly person is adhering to their medication schedule."
This is an important issue since controlling chronic diseases such as diabetes and high blood pressure requires medication to be taken and at the right times.
The monitoring of pillbox use has also uncovered helpful information that was not anticipated. Dr. Tan recalls the case of a woman who had been using the pillbox frequently in the middle of the night. "We thought something must be wrong," Dr. Tan recounts.
The researchers informed caregivers, who then spoke to the tenant. They discovered that the lady was suffering from insomnia and leg pain, and hence was taking painkillers from the pillbox in the middle of the night to relieve the pain. She would also repack her medication in the pillbox when she couldn't sleep, creating a false response that the pillbox was used frequently." With the truth uncovered, caregivers could better help the lady with her conditions.
After its three-year trial, there are hopes that the implementation of the smart home systems will be scaled up throughout Singapore. In the interim, improvements have been made to increase the effectiveness of the technology. For instance, the system's interface has been redesigned to provide information to caregivers in a more usable form, while VWOs now receive alerts directly, without researchers acting as intermediaries.
Responses from elderly participants have also been encouraging. No one has dropped out of Project SHINESeniors, and many seniors have also urged their friends to sign up for the pilot test.
"What touches me most," says Dr. Tan, "is to hear from the elderly that the system makes them feel safe."

Provided by ResearchSEA 

Tuesday, October 29, 2019

Neck circumference of the elderly is associated with their nutritional status

Neck circumference of the elderly is associated with their nutritional status
Researchers have discovered that the circumference of the neck serves as a reference to detect possible cases of malnutrition. Credit: Beatriz Lardiés
Researchers at the Miguel Servet University Hospital in Zaragoza (Spain) have analysed the ratio between the perimeter of the neck of people living in old people's homes and the probability of malnutrition. Values below 37.8 cm in males and 35.2 cm in females indicate risk.
29 oct 2019--Professionals working in nursing homes often detect possible cases of malnutrition by measuring certain body circumferences of the elderly, such as the arm or calf. Now, a team of researchers from Zaragoza has found another part of the body that can serve as a reference: the neck.
To carry out their study, the authors cross-checked the anthropometric data of 352 elderly people from five public homes in Zaragoza and with an average age of 83, with their results in a questionnaire called Mini Nutritional Assessment (MNA). This assessment tool is commonly used to identify malnourished elderly people or those at risk of being malnourished.
Statistical methods were then applied to find the association between these two parameters, and the results, published in the journal Nutrition, confirm that the circumference of the neck -together with that of the calf- presents the best predictive value when diagnosing the risk of malnutrition among residents.
"In our study, the cut-off point for detecting the risk of malnutrition was 37.8 cm in men and 35.2 cm in women, a limit to be taken into account by the staff of the homes," says Beatriz Lardiés, a researcher at the Miguel Servet University Hospital and co-author of the study.
Once the risk of malnutrition—which affected 48.3% of the women and 45.5% of the men analysed—is detected, it is necessary to carry out a complete nutritional assessment and to consider other clinical and analytical parameters in order to check whether a patient is really malnourished. If this turns out to be the case, the necessary measures to reverse this situation should be taken immediately.
"The diagnosis of malnutrition cannot be made with a single anthropometric parameter, like the perimeter of the calf or the circumference of the arm, but it can help identify it," Lardiés says.
The researcher points out that, as this study has been carried out in nursing homes, "its results can be extrapolated to populations with similar characteristics, but we cannot ensure that the cut-off points detected are valid in other population groups."
In any case, the authors conclude that anthropometry is an easy and non-invasive method for rapidly assessing the nutritional status of older people, a group that is growing all over the world.

More information: Beatriz Lardiés-Sánchez et al. Neck circumference is associated with nutritional status in elderly nursing home residents, Nutrition (2019). DOI: 10.1016/j.nut.2019.01.015
Provided by Plataforma SINC 

Thursday, October 24, 2019

Bed time is the best time to take blood pressure medication

Bed time is the best time to take blood pressure medication
Adjusted hazard ratio (95% CI) of cardiovascular events as a function of hypertension treatment-time (either upon awakening or at bedtime). Total events: Death from all causes, myocardial infarction, coronary revascularization, heart failure, ischaemic and haemorrhagic stroke, angina pectoris, peripheral artery disease, thrombotic occlusion of the retinal artery, and transient ischaemic attack. Coronary events: cardiovascular disease death, myocardial infarction, and coronary revascularization. Cardiac events: Coronary events and heart failure. cardiovascular disease-outcome: Cardiac events plus ischaemic and haemorrhagic stroke. Minor events: angina events, peripheral artery disease, thrombotic occlusion of the retinal artery, and transient ischaemic attack. Credit: European Heart Journal
People with high blood pressure who take all their anti-hypertensive medication in one go at bedtime have better controlled blood pressure and a significantly lower risk of death or illness caused by heart or blood vessel problems, compared to those who take their medication in the morning, according to new research.
24 oct 2019--The Hygia Chronotherapy Trial, which is published in the European Heart Journal today, is the largest to investigate the effect of the time of day when people take their anti-hypertensive medication on the risk of cardiovascular problems. It randomised 19,084 patients to taking their pills on waking or at bedtime, and it has followed them for the longest length of time—an average of more than six years—during which time the patients' ambulatory blood pressure was checked over 48 hours at least once a year.
The researchers, who are part of the Hygia Project led by Professor Ramón C. Hermida, Director of the Bioengineering and Chronobiology Labs at the University of Vigo, Spain, found that patients who took their medication at bedtime had nearly half the risk (45% reduction) of dying from or suffering heart attacks, myocardial infarction, stroke, heart failure or requiring a procedure to unblock narrowed arteries (coronary revascularisation), compared to patients who took their medication on waking.
The researchers had adjusted their analyses to take account of factors that could affect the results, such as age, sex, type 2 diabetes, kidney disease, smoking and cholesterol levels.
When they looked at individual outcomes, they found that the risk of death from heart or blood vessel problems was reduced by 66%, the risk of myocardial infarction was reduced by 44%, coronary revascularisation by 40%, heart failure by 42%, and stroke by 49%.
Prof Hermida said: "Current guidelines on the treatment of hypertension do not mention or recommend any preferred treatment time. Morning ingestion has been the most common recommendation by physicians based on the misleading goal of reducing morning blood pressure levels. However, the Hygia Project has reported previously that average systolic blood pressure when a person is asleep is the most significant and independent indication of cardiovascular disease risk, regardless of blood pressure measurements taken while awake or when visiting a doctor. Furthermore, there are no studies showing that treating hypertension in the morning improves the reduction in the risk of cardiovascular disease.
"The results of this study show that patients who routinely take their anti-hypertensive medication at bedtime, as opposed to when they wake up, have better-controlled blood pressure and, most importantly, a significantly decreased risk of death or illness from heart and blood vessel problems."
The Hygia Project is composed of a network of 40 primary care centres within the Galician Social Security Health Service in northern Spain. A total of 292 doctors are involved in the project and have been trained in ambulatory blood pressure monitoring, which involves patients wearing a special cuff that records blood pressure at regular intervals throughout the day and night. The Hygia Chronotherapy Trial is unusual in monitoring blood pressure for 48 hours, rather than the more usual 24 hours.
Between 2008 and 2018, 10,614 men and 8,470 women of Caucasian Spanish origin, aged 18 or over, who had been diagnosed with hypertension by means of ambulatory blood pressure monitoring, were recruited to the trial; they had to adhere to a routine of daytime activity and night-time sleep, which means that it is not possible to say if the study findings apply to people working night shifts.
Doctors took the patients' blood pressure when they joined the study and at each subsequent clinic visit. Ambulatory blood pressure monitoring over a 48-hour period took place after each clinic visit and at least once a year. This gave doctors accurate information on average blood pressures over the 48 hours, including how much blood pressure decreased or 'dipped' while the patients were asleep.
During a median (average) of 6.3 years follow-up, 1752 patients died from heart or blood vessel problems, or experienced myocardial infarction, stroke, heart failure or coronary revascularisation. Data from ambulatory blood pressure monitoring showed that patients taking their medication at bedtime had significantly lower average blood pressure both at night and during the day, and their blood pressure dipped more at night, when compared with patients taking their medication on waking. A progressive decrease in night-time systolic blood pressure during the follow-up period was the most significant predictor of a reduced risk of cardiovascular disease.
Prof Hermida concluded: "The findings from the Hygia Chronotherapy Trial and those previously reported from the Hygia Project indicate that average blood pressure levels while asleep and night-time blood pressure dipping, but not day-time blood pressure or blood pressure measured in the clinic, are jointly the most significant blood pressure-derived markers of cardiovascular risk. Accordingly, round-the-clock ambulatory blood pressure monitoring should be the recommended way to diagnose true arterial hypertension and to assess the risk of cardiovascular disease. In addition, decreasing the average systolic blood pressure while asleep and increasing the sleep-time relative decline in blood pressure towards more normal dipper blood pressure patterns are both significantly protective, thus constituting a joint novel therapeutic target for reducing cardiovascular risk."
The Hygia Project is currently investigating what the best blood pressure levels should be while asleep in order to reduce cardiovascular risk most effectively in the THADEUS Trial (Treatment of Hypertension During Sleep).
Limitations of the Hygia Chronotherapy Trial include that it requires validation in other ethnic groups; the question of whether the same results would be seen in shift workers also requires investigation; and patients were not assigned to specific hypertension medication classes or specific lists of medications within each class—their treatment was chosen by their doctors according to current clinical practice.

More information: Ramón C Hermida et al, Bedtime hypertension treatment improves cardiovascular risk reduction: the Hygia Chronotherapy Trial, European Heart Journal (2019). DOI: 10.1093/eurheartj/ehz754
Ramón C Hermida et al. Asleep blood pressure: significant prognostic marker of vascular risk and therapeutic target for prevention, European Heart Journal (2018). DOI: 10.1093/eurheartj/ehy475
Journal information: European Heart Journal 
Provided by European Society of Cardiology 

Monday, October 21, 2019

Frailty: The rising global health burden for an aging society

aging
Credit: CC0 Public Domain
Despite the evidence on risk factors for frailty, and the substantial progress that has been made in frailty awareness, the biological mechanisms underlying its development are still far from understood and translation from research to clinical practice remains a challenge, according to a new series on Frailty just published by The Lancet.
21 oct 2019--Linda P. Fried, MD, MPH, dean of Columbia University Mailman School of Public Health and DeLamar Professor of Public Health Practice, and Professor of Epidemiology and Medicine, was part of an international group of experts who contributed to the series of papers which provide an up-to-date clinical overview on preventing, identifying and managing frailty as well as its global impact and burden. The series also offers evidence-based interventions for individuals with frailty. The findings are published online.
In the paper on Clinical Practice and Public Health, Fried, a renowned gerontologist and expert on aging, highlights two emerging lines of life course evidence on frailty. First, Fried and colleagues make the point that the risk of adverse outcomes can be predicted. Secondly, there is a clinical syndrome of frailty which is an outcome of biologic aging, although risk levels are substantially higher among those with certain diagnoses and comorbidities. She also notes that while great strides have been made in understanding frailty in the past two decades, many gaps in knowledge remain: no universal consensus exists on the definition of frailty or its assessment, and more robust, high-quality trials of strategies to prevent and manage frailty are needed.

More information: Emiel O Hoogendijk et al, Frailty: implications for clinical practice and public health, The Lancet (2019). DOI: 10.1016/S0140-6736(19)31786-6
Journal information: The Lancet 
Provided by Columbia University's Mailman School of Public Health 

Non-pharmacologic treatments may be more effective for psychiatric symptoms of dementia

DEMENTIA
Credit: CC0 Public Domain
For patients with dementia who have symptoms of aggression and agitation, interventions such as outdoor activities, massage and touch therapy may be more effective treatments than medication in some cases, suggests a study publishing Oct. 14 in Annals of Internal Medicine.
21 oct 2019--The systematic review and meta-analysis, led by St. Michael's Hospital of Unity Health Toronto and the University of Calgary, suggest outdoor activities were more clinically effective than anti-psychotic medication for treating physical aggression in patients with dementia. For patients with physical agitation, massage and touch therapy were more efficacious than usual care or caregiver support.
"Dementia affects 50 million people worldwide and as many as three quarters of those living with the disease have reported neuropsychiatric symptoms including aggression, agitation and anxiety," said Dr. Jennifer Watt, a researcher at the Li Ka Shing Knowledge Institute of St. Michael's Hospital.
"Unfortunately, our understanding of the comparative efficacy of medication versus non-medicine interventions for treating psychiatric symptoms has been limited due to a lack of head-to-head randomized controlled trials of the two routes."
To address this gap, researchers led by Dr. Watt, who is also a geriatrician; Dr. Sharon Straus, director of the Knowledge Translation Program at St. Michael's; and Dr. Zahra Goodarzi, a geriatrician and researcher at the University of Calgary, worked with 12 dementia care partners to select study outcomes based on commonly reported neuropsychiatric symptoms of the disease. They identified reports of improvement in aggression and agitation to be the main two outcomes to focus on in the analysis and review.
The study's findings are based on an analysis of 163 randomized controlled trials involving 23,143 people with dementia and the study of pharmacologic or non-pharmacologic interventions to treat aggression and agitation.
Though the study allows for the comparison of the two types of interventions, the researchers point out that neuropsychiatric symptoms of dementia do not have a one-size-fits-all solution.
"Treatment should be tailored to the patient and their specific experience," said Dr. Straus, who is also a geriatrician at St. Michael's. "This study, however, does shed light on the opportunity to consider prioritizing different types of interventions for aggression and agitation when appropriate."
Further research, Dr. Watt said, will aim to understand the influence of individual patient characteristics on their response to interventions. The researchers also note the need for an analysis of the differences in cost between pharmacologic and non-pharmacologic interventions to treat aggression and agitation in patients with dementia.
"This study shows us that multidisciplinary care is efficacious, and that is consistent with a person-centred approach to care," Dr. Watt said. "It points to evidence of the benefit of supporting multidisciplinary teams providing care to patients in the community and nursing home settings."

More information: Annals of Internal Medicine (2019). http://annals.org/aim/article/doi/10.7326/M19-0993
Journal information: Annals of Internal Medicine 
Provided by St. Michael's Hospital 

Sunday, October 13, 2019

With AGS Cocare, HELP, AGS expands reach of seminal delirium prevention program


elderly
Credit: CC0 Public Domain
A seminal program for preventing delirium (the medical term for abrupt, rapid-onset confusion or altered mental state, affecting millions of older adults annually) and loss of function for hospitalized older adults stands poised for a major expansion thanks to the American Geriatrics Society (AGS). As the soon-to-be newest addition to the AGS "CoCare" portfolio, a suite of programs helping embed geriatrics expertise in broader care for older adults, AGS CoCare: HELP represents a new step forward for a program that has already taken significant strides.
13 oct 2019--"Empowering health systems to recognize, manage, and prevent delirium is one of the hallmarks of geriatrics, one that put the specialty on the map," notes Sharon K. Inouye, MD, MPH, who developed the original Hospital Elder Life Program (HELP), now known as AGS CoCare: HELP. "With this critical expansion of a key program that made delirium prevention possible, we now have bandwidth through the AGS to demonstrate to more health systems than ever before how collaborating with geriatrics leads to improved health, safety, and independence for us all," Dr. Inouye concluded.
Through AGS CoCare: HELP (which will launch later this year at help.agscocare.org), more health systems than ever before will have access to tools and hands-on guidance for making delirium prevention actionable locally and for individual patients. Institutional subscriptions offer access to a comprehensive implementation toolkit, an online educational curriculum for HELP staff and volunteers, a certification program, scheduling for routine coaching calls, and access to an online community available 24-7.
Perhaps more importantly, they also help standardize best practices while supporting work to keep these practices at the cutting-edge of delirium-prevention science. The program ultimately promotes a growing trend toward "age-friendly health systems" in the U.S.—so named because they help promote unique expertise on geriatrics focal points, such as care for the mind, medications, mobility, and what "matters most" to patients as people.
And behind it all is an evidence-based program with decades of experience and proven results improving the health and care of hospitalized older adults.
For millions of older adults, HELP has made health systems safer—and health care more effective. Delirium affects more than 2.6 million older adults per year in the U.S., accounting for more than $164 billion annually in excess Medicare expenditures. HELP set out to change that—and did so with resounding success. On average, delirium cases dropped by more than 30 percent among the more than 200 hospitals employing HELP, which also reduced costs by more than $7 million annually at participating hospitals (a savings of more than $1,000 per patient).
According to Dr. Inouye, HELP's success rests on its streamlined, stepwise approach, particularly when it comes to embedding fundamental geriatrics principles into the fabric of existing care structures.
"To the untrained eye, delirium can happen without warning—but there are tell-tale signs that point to risk, and proven interventions to reduce its likelihood," Dr. Inouye observes. "Health systems just need to know how, which is where HELP offers critical assistance."
HELP does so by providing an organized system to manage markers of delirium and delirium prevention—from maintaining physical and cognitive function to maximizing independence in the transition from hospital to home. This system includes training to understand the value and practical implementation of daily patient visits, therapeutic activities, early mobilization programs, protocols to optimize sleep and hearing/vision, and opportunities for smoothing transitions between care settings. Using comprehensive HELP resources and training, whole health systems can implement delirium prevention protocols, provider education, and audio-visual tools, while individual HELP staff and a network of specially trained volunteers can work with patients one-on-one to reduce personal risks and prevent lengthier stays.
Soon to be available 24-7 at help.agscocare.org, AGS CoCare: HELP joins an established roster of AGS programs to increase collaboration between geriatrics experts and their colleagues. AGS CoCare: Ortho, the first in the AGS CoCare series, for example, has been implemented at health systems across the U.S. to improve health outcomes for older adults hospitalized with hip fractures.
More information: For more information, visit AmericanGeriatrics.org/Programs/AGS-CoCare-HELPTM.
Provided by American Geriatrics Society 

Slower walkers have older brains and bodies at 45

Slower walkers have older brains and bodies at 45
A long-term study has found that signs of aging may be detected by a simple walking test at age 45, and that the brains of slower walkers were different at age 3. Credit: Duke University Communications
The walking speed of 45-year-olds, particularly their fastest walking speed without running, can be used as a marker of their aging brains and bodies.
13 oct 2019--Slower walkers were shown to have "accelerated aging" on a 19-measure scale devised by researchers, and their lungs, teeth and immune systems tended to be in worse shape than the people who walked faster.
"The thing that's really striking is that this is in 45-year-old people, not the geriatric patients who are usually assessed with such measures," said lead researcher Line J.H. Rasmussen, a post-doctoral researcher in the Duke University department of psychology & neuroscience.
Equally striking, neurocognitive testing that these individuals took as children could predict who would become the slower walkers. At age 3, their scores on IQ, understanding language, frustration tolerance, motor skills and emotional control predicted their walking speed at age 45.
"Doctors know that slow walkers in their seventies and eighties tend to die sooner than fast walkers their same age," said senior author Terrie E. Moffitt, the Nannerl O. Keohane University Professor of Psychology at Duke University, and Professor of Social Development at King's College London. "But this study covered the period from the preschool years to midlife, and found that a slow walk is a problem sign decades before old age."
The data come from a long-term study of nearly 1,000 people who were born during a single year in Dunedin, New Zealand. The 904 research participants in the current study have been tested, quizzed and measured their entire lives, mostly recently from April 2017 to April 2019 at age 45.
The study appears Oct. 11 in JAMA Network Open.
MRI exams during their last assessment showed the slower walkers tended to have lower total brain volume, lower mean cortical thickness, less brain surface area and higher incidence of white matter "hyperintensities," small lesions associated with small vessel disease of the brain. In short, their brains appeared somewhat older.
Adding insult to injury perhaps, the slower walkers also looked older to a panel of eight screeners who assessed each participant's 'facial age' from a photograph.
Gait speed has long been used as a measure of health and aging in geriatric patients, but what's new in this study is the relative youth of these study subjects and the ability to see how walking speed matches up with health measures the study has collected during their lives.
"It's a shame we don't have gait speed and  imaging for them as children," Rasmussen said. (The MRI was invented when they were five, but was not given to children for many years after.)
Some of the differences in health and cognition may be tied to lifestyle choices these individuals have made. But the study also suggests that there are already signs in early life of who would become the slowest walkers, Rasmussen said. "We may have a chance here to see who's going to do better health-wise in later life."

More information: "Association of Neurocognitive and Physical Function With Gait Speed in Midlife," Line Rasmussen, Avshalom Caspi, Anthony Ambler, et al. .JAMA Network Open, Oct. 11, 2019. DOI: 10.1001/jamanetworkopen.2019.13123
Journal information: JAMA Network Open 
Provided by Duke University 

Six minutes of walking can increase motivation to perform physical activity

walking
Credit: CC0 Public Domain
Just six minutes of walking can increase a person's motivation to perform physical activity and improve feelings of energy, fatigue, depression, and confusion, according to research conducted by Clarkson University Associate Professor in Physical Therapy, Ali Boolani.
13 oct 2019--Boolani recently completed a study where he measured the mood of patients over the age of 65 before and after taking a six minute walk, and found that patients saw decreased mental fatigue and improved physical energy after their walk.
Patients were asked to participate in a three-day study. On the first day, Boolani and his team measured their moods, had them walk around, and measured their moods again. On days two and three, the patients were given cognitive tasks that were meant to make them feel worse, after which their mood was measured. Then, it was time for a walk.
We had them walk for six minutes around a track, and we had them walk at a pace that they felt comfortable with," Boolani said. "Even on the days they did cognitive tasks they started feeling better, and they even got up above baseline, which was really cool."
Levels of anxiety in patients were also found to decrease, according to Boolani.
"Feelings of anxiety definitely improved, this is along the lines of most of the studies that have been done that show that physical activity improves feelings of anxiety," he said.
On top of an increase in physical energy and a decrease in mental , Boolani measured patients' motivation levels.
"Turns out, after six minutes of physical activity, they were more motivated to perform physical tasks," He said. "In a real setting if you're having a tough day, you don't feel like working out, maybe six minutes of just walking can make you more motivated to be more physically active."
According to Boolani, similar studies have been conducted in the past, but six minutes is the shortest amount of time anyone has tested the impact of walking.
He also said the pace at which patients walked had an impact on their energy and fatigue levels.
"The faster they walked, the more their feelings of energy increased and their  of fatigue decreased," Boolani said.

Provided by Clarkson University 

Dog ownership associated with longer life, especially among heart attack and stroke survivors


dog
Credit: CC0 Public Domain
Dog ownership may be associated with longer life and better cardiovascular outcomes, especially for heart attack and stroke survivors who live alone, according to a new study and a separate meta-analysis published in Circulation: Cardiovascular Quality and Outcomes, a journal of the American Heart Association.
13 oct 2019--"The findings in these two well-done studies and analyses build upon prior studies and the conclusions of the 2013 AHA Scientific Statement 'Pet Ownership and Cardiovascular Risk' that dog ownership is associated with reductions in factors that contribute to cardiac risk and to cardiovascular events," said Glenn N. Levine, M.D., chair of the writing group of the American Heart Association's scientific statement on pet ownership. "Further, these two studies provide good, quality data indicating dog ownership is associated with reduced cardiac and all-cause mortality. While these non-randomized studies cannot 'prove' that adopting or owning a dog directly leads to reduced mortality, these robust findings are certainly at least suggestive of this."
Given previous research demonstrating how social isolation and lack of physical activity can negatively impact patients, researchers in both the study and meta-analysis sought to determine how dog ownership affected health outcomes. Prior studies have shown that dog ownership alleviates social isolation, improves physical activity and even lowers blood pressure—leading researchers to believe dog owners could potentially have better cardiovascular outcomes compared to non-owners.
Dog ownership and survival after a major cardiovascular event—a registry-based, prospective study
Researchers in this study compared the health outcomes of dog owners and non-owners after a heart attack or stroke using health data provided by the Swedish National Patient Register. Patients studied were Swedish residents ages 40-85 who experienced heart attack or ischemic stroke from 2001-2012.
Compared to people who did not own a dog, researchers found that for dog owners:
  • The risk of death for heart attack patients living alone after hospitalization was 33% lower, and 15% lower for those living with a partner or child.
  • The risk of death for stroke patients living alone after hospitalization was 27% lower and 12% lower for those living with a partner or child.
In the study, nearly 182,000 people were recorded to have had a heart attack, with almost 6% being dog owners, and nearly 155,000 people were recorded to have had an ischemic stroke, with almost 5% being dog owners. Dog ownership was confirmed by data from the Swedish Board of Agriculture (registration of dog ownership has been mandatory since 2001) and the Swedish Kennel Club (all pedigree dogs have been registered since 1889).
The lower risk of death associated with dog ownership could be explained by an increase in physical activity and the decreased depression and loneliness, both of which have been connected to dog ownership in previous studies.
"We know that social isolation is a strong risk factor for worse health outcomes and premature death. Previous studies have indicated that dog owners experience less social isolation and have more interaction with other people," said Tove Fall, D. V. M., professor at Uppsala University in Sweden. "Furthermore, keeping a dog is a good motivation for physical activity, which is an important factor in rehabilitation and mental health."
While this study draws from a large sample, potential misclassifications of dog ownership in couples living together, death of a dog and change of ownership could have affected the outcomes of the study.
"The results of this study suggest positive effects of dog ownership for patients who have experienced a heart attack or stroke. However, more research is needed to confirm a causal relationship and giving recommendations about prescribing dogs for prevention. Moreover, from an animal welfare perspective, dogs should only be acquired by people who feel they have the capacity and knowledge to give the pet a good life."
Co-authors of the study are Mwenya Mubanga, M.D., M.P.H.; Liisa Byberg, Ph.D.; Agneta Egenvall, V.M.D., Ph.D.; Erik Ingelsson, MD, Ph.D. and Tove Fall, V.M.D., Ph.D. Agria Research Foundation and the Swedish Research Council for Environment, Agricultural Sciences and Spatial Planning (FORMAS), grant number 2013-1673 funded the study.
Dog Ownership and Survival: A Systematic Review and Meta-Analysis
Researchers reviewed patient data of over 3.8 million people taken from 10 separate studies for a composite meta-analysis study. Of the 10 studies reviewed, nine included comparison of all-cause mortality outcomes for dog owners and non-owners, and four compared cardiovascular outcomes for dog owners and non-owners.
Researchers found that compared to non-owners, dog owners experienced a:
  • 24% reduced risk of all-cause mortality;
  • 65% reduced risk of mortality after heart attack; and
  • 31% reduced risk of mortality due to cardiovascular-related issues.
"Having a dog was associated with increased physical exercise, lower blood pressure levels and better cholesterol profile in previous reports," said Caroline Kramer, M.D. Ph.D., Assistant Professor of Medicine at the University of Toronto and an Endocrinologist and Clinician scientist at Leadership Sinai Centre for Diabetes at Mount Sinai Hospital, part of Sinai Health System. "As such, the findings that people who owned  lived longer and their risk for cardiovascular death was also lower are somewhat expected."
Studies deemed eligible for analysis included those conducted among adults age 18 or older, original data from an original prospective study, evaluated dog ownership at the beginning of the study and reported all-cause or cardiovascular mortality of patients. Studies were excluded if they were retrospective, did not provide an absolute number of events that occurred and reported non-fatal cardiovascular events.
"Our findings suggest that having a dog is associated with longer life. Our analyses did not account for confounders such as better fitness or an overall healthier lifestyle that could be associated with dog ownership. The results, however, were very positive," said Dr. Kramer. "The next step on this topic would be an interventional study to evaluate cardiovascular outcomes after adopting a dog and the social and psychological benefits of dog ownership. As a dog owner myself, I can say that adopting Romeo (the author's miniature Schnauzer) has increased my steps and physical activity each day, and he has filled my daily routine with joy and unconditional love."

More information: Circulation: Cardiovascular Quality and Outcomes (2019). DOI: 10.1161/CIRCOUTCOMES.118.005342
Journal information: Circulation: Cardiovascular Quality and Outcomes 
Provided by American Heart Association 

Is 5G bad for your health? It's complicated, say researchers



Is 5G bad for your health? It’s complicated, say researchers
The radiation emitted by 5G will largely be the same as previous networks, except that it will be exposing us to something called milimetre waves for the first time. Credit: Flickr/ Kārlis Dambrāns, licensed under CC BY 2.0
Countries such as Switzerland, the UK and Germany are already rolling out next generation networks. 5G is projected to be 100 times faster than 4G and would allow new technologies such as connected cars and augmented reality to flourish. But despite the big promises, concerns about its potential health effects are also growing.
13 OCT 2019--In September 2017, doctors and scientists launched the 5G Appeal, a petition which calls for the EU to impose a moratorium on 5G rollout, citing imminent health dangers like increased cancer risks, cellular stress and genetic damage. The petition now has more than 250 signatories. In March this year, then Brussels minister of environment Céline Fremault blocked a 5G rollout saying she wouldn't turn the city's inhabitants into 'laboratory mice." In Bern, Switzerland, a protest in May led some administrative areas to block the construction of 5G antennas.
So how different is 5G and could it impact our health? The reality, experts say, is complex.
"We have been involved in hundreds of studies about electromagnetic radiation and human health," said Professor Niels Kuster, founder and director of the Swiss IT"IS Foundation. He was project coordinator for ARIMMORA, a study into the relation between the electromagnetic radiation emitted by power lines and childhood leukaemia.
Both mobile phones and telecom antennas emit electromagnetic radiation, regardless of what network generation they are used for. They send out non-ionising radiation, which is located at the lower end of the frequency spectrum. Most electrical gear emits this type of radiation, from microwave ovens to power lines.
Non-ionising radiation has completely different health effects from ionising radiation, which is higher up the spectrum and includes X-Rays or nuclear radiation, which have proven harmful effects for human health.
Radiation
Non-ionising radiation can affect us in two ways, according to Prof. Kuster. Just like a microwave oven heats food using non-ionising radiation, telecom gear can do the same to the human body if it emits too much.
"That's well understood scientifically and there are clear safety guidelines for this," he said. The International Commission on Non-Ionizing Radiation Protection (ICNIRP), a global scientific body, for example, has determined a norm for this and continually monitors thermal effects.
We have less of an understanding of the second way in which non-ionising radiation can affect us—how it interferes with us biologically, says Prof. Kuster.
There have been claims that telecom equipment causes cancer and electrohypersensitivity where people experience headaches, nausea or even rashes they believe to be the result of exposure to electromagnetic radiation.
Prof. Kuster says that there is very little clear scientific evidence showing that radiation causes the exhibited symptoms associated with electrohypersensitivity. The World Health Organization noted that double-blind studies have been unable to establish a correlation.
The evidence around cancer is, however, more difficult to interpret. Several large-scale epidemiological studies showed mixed results.
The most well-known is probably the 13-country Interphone study from 2000 to 2006 with around 5,000 patients. This tried to find a correlation between mobile phone use and cancer.
It concluded that 'no increase in risk of glioma or meningioma was observed with use of mobile phones." For people who used mobile phones more intensively at that time, however, there were 'suggestions' of higher glioma rates, but errors and biases could not be ruled out, so no causal relationship could be established.
Some animal or lab-based cell studies have shown certain negative health effects from radiation. This eventually led the International Agency for Research on Cancer (IARC) to classify electromagnetic radiation as 'possibly carcinogenic to humans."
This may sound scary but refers largely to uncertainty in the results. Aloe vera leaves, for example, are in the same category. Working at a barber shop is in a higher category, classified as 'probably carcinogenic to humans' because of the chemicals hairdressers interact with.
Tracking
Other studies are happening right now, such as COSMOS, which is being carried out in the Netherlands, Sweden, Finland, the UK, Denmark and France.
"In total we're tracking 290,000 people across Europe, who we consult every five years," said Professor Hans Kromhout, an epidemiologist at Utrecht University in the Netherlands who works on the Dutch chapter of COSMOS.
They use information from mobile phone operators to track consenting participants' actual phone use, and then relate that to health outcomes. This was necessary as from previous studies, it became clear that participants have difficulties accurately reporting their own phone usage.
"The data for cancer we don't have yet," said Prof. Kromhout. "But we recently released a study for Sweden and Finland, which found an association between frequent phone use and headaches." But it unlikely due to radiofrequency electromagnetic fields, he adds.
This study looked at 21,049 Swedes and 3,120 Finns, and tried correlating phone use with headaches, sinusitis and hearing problems. Participants who called more than 276 minutes per week reported a slightly higher degree of weekly headaches. But it turned out that participants who had 2G-phones (which emit more radiation) did not have a higher degree of headaches than those with 3G-phones (which emit less radiation).
And if a clear association between this kind of radiation and cancer was found, an underlying cause would still be missing since we don't understand the potential biological effects, according to Prof. Kromhout.
"We still don't have a mechanism to explain why the human body would have this reaction," said Prof. Kromhout. "And without a biological mechanism you cannot have a clear, causal relation, because it could just as well be that something else is causing the cancer."
Millimetre waves
Ever since we've had mobile phones, there have been concerns about their negative health effects. In most areas, the 5G debate is a continuation of all of this, which is logical. The radiation 5G emits will largely be the same as it was for 4G, 3G and 2G before, except for one area: millimetre waves.
These waves are higher up the spectrum than the frequencies we have so far used for mobile telecommunications, although they are still non-ionising radiation.
Milimetre waves are a sub-technology of 5G, which can transfer more information, although for shorter distances. For now, these frequencies aren't being implemented or even auctioned in Europe, although in the US operators have been using them to build their 5G networks. There has been little research about their health effects.
We know, for example, that they don't penetrate our skin as much as lower frequency waves, yet that could also mean a different risk assessment, with more attention placed on the skin.
"I don't claim we need to be concerned about millimetre wave exposure," said Prof. Kuster. "But it's irresponsible to not have much data and expose large groups of people to these fields. So, there should be more investment into tests about this."
An argument often used against this sort of research though, is that it's influenced by the private sector. Telecom companies, according to activists, often fund this research to influence it in their direction. Prof. Kuster accepts private sector funds, and in Sweden, COSMOS is partly funded by a number of mobile phone operators, with a scientific institute acting as a 'firewall' between the researchers and the companies.
He says that the results of a study don't depend on where the money came from but on the quality of the research.
"It would be good if public institutions invested more in research into these fields," said Prof. Kromhout, whose COSMOS study is funded by the Dutch government. "That way we can also put to rest doubts about the objectivity of researchers."
Until now the EU has funded some research on electromagnetic radiation, but currently there is no EU project focusing on the health effects of 5G.
So if we aren't certain about 5G's health effects, shouldn't we just ban it until we are and apply the precautionary principle? Not according to both experts.
"That would be too much," said Prof. Kromhout. "We should keep studying and observing this question and be vigilant. But a complete ban would be too much and stop technological innovation. We also haven't seen a large rise of brain cancer in the last 20 years, even though cell phone use has exploded."
Prof. Kuster also argues for more scientific research. "As long as there is no consensus in the scientific world, there won't be one in politics," he said. "As long as the effects are unclear, the debate will continue."

Provided by Horizon: The EU Research & Innovation Magazine