Randomized trials show it doesn't reduce pain or pain-related disability compared to placebo
In one study, David F. Kallmes, M.D., of the Mayo Clinic in Rochester, Minn., and colleagues randomly assigned 131 patients to receive either vertebroplasty or a simulated procedure without cement. They found no significant group differences in the primary outcomes -- scores on the modified Roland-Morris Disability Questionnaire and patient ratings of average pain intensity on a scale of zero to 10 -- after one month. In a second study, Rachelle Buchbinder, Ph.D., of Monash University in Malvern, Australia, and colleagues randomly assigned 78 patients to receive either vertebroplasty or a sham procedure. They found no significant group differences in the primary outcome -- overall pain on a scale of zero to 10 -- after three months. "Given the increasing use, limited benefit, and potential risk, how often should vertebroplasty be performed?" asks the author of an accompanying editorial. "When best evidence suggests a toss-up between treatment options and no benefit, informed patient choice is essential. When faced with several choices for which the evidence is less than clear, patients and doctors must thoroughly review the options together." Authors of both studies reported financial relationships with pharmaceutical and medical companies. Abstract - Kallmes
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Abstract - Buchbinder
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2 comments:
There's a lot more info out there supporting the positives of Vertebroplasty:
It is the position of the American Society of Interventional and Therapeutic Neuroradiology, Society of Interventional Radiology, American Association of Neurological Surgeons/Congress of Neurological Surgeons, and American Society of Spine Radiology (“the Societies”) that percutaneous vertebral augmentation with vertebroplasty and kyphoplasty is a safe, efficacious, and durable procedure in appropriate patients with symptomatic osteoporotic and neoplastic fractures when performed in a manner in accordance with published standards.
Read the article:
http://www.jvir.org/article/PIIS1051044307003120/fulltext
There's a lot more info out there supporting the positives of Vertebroplasty:
It is the position of the American Society of Interventional and Therapeutic Neuroradiology, Society of Interventional Radiology, American Association of Neurological Surgeons/Congress of Neurological Surgeons, and American Society of Spine Radiology (“the Societies”) that percutaneous vertebral augmentation with vertebroplasty and kyphoplasty is a safe, efficacious, and durable procedure in appropriate patients with symptomatic osteoporotic and neoplastic fractures when performed in a manner in accordance with published standards.
Read the article:
http://www.jvir.org/article/PIIS1051044307003120/fulltext
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